Now that you are somewhat familiar with some of the main concepts in human genetics (thanks to the crash course in the previous post), we are ready to start talking about the analytical challenges of statistical genetics, and finally start delving into the open problems listed in the first post. At this point, you should …
Continue reading “Genetic association studies: not as simple as you might think”
The purpose of this post is to lay out some basic concepts and background in human genetics, which we’ll need to discuss the challenges in the field. If you are already familiar with molecular biology and want to jump straight ahead to the challenges, feel free to skip or gloss over this post. As we’ll …
A data scientist’s guide to statistical genetics Our genetics shapes almost every part of ourselves we care about: how we look and behave, what we are good or bad at, and which medical conditions we are most likely to encounter in life. Virtually all top causes of disease burden in developed countries, whether it’s cancer, …
Continue reading “Understanding the genetic basis of the human condition – 16 analytical challenges”